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1

Development of a P-glycoprotein knockout model in rodents to define species differences in its functional effect at the blood–brain barrier

Leanne Cutler, Colin Howes, Nigel J. Deeks, Tania L. Buck, Phil Jeffrey

Journal:

Journal of Pharmaceutical Sciences

Year:

2006

Language:

english

File:

PDF, 219 KB

english, 2006

2

Detection of microRNA biomarkers via inhibition of DNA-mediated liposome fusion

Jumeaux, Coline, Kim, Eunjung, Howes, Philip D., Kim, Hyemin, Chandrawati, Rona, Stevens, Molly M.

Journal:

Nanoscale Advances

Year:

2019

Language:

english

File:

PDF, 1.03 MB

english, 2019

3

Synthesis and biological properties of novel glucocorticoid androstene C-17 furoate esters

David A. Sandham, Lucy Barker, David Beattie, David Beer, Louise Bidlake, David Bentley, Keith D. Butler, Sarah Craig, David Farr, Claire Ffoulkes-Jones, John R. Fozard, Sandra Haberthuer, Colin Howes

Journal:

Bioorganic & Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 410 KB

english, 2004

4

Second generation of BACE-1 inhibitors part 3: Towards non hydroxyethylamine transition state mimetics

Nicolas Charrier, Brian Clarke, Leanne Cutler, Emmanuel Demont, Colin Dingwall, Rachel Dunsdon, Julie Hawkins, Colin Howes, Julia Hubbard, Ishrut Hussain, Graham Maile, Rosalie Matico, Julie Mosley, A

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 696 KB

english, 2009

5

Second generation of BACE-1 inhibitors. Part 1: The need for improved pharmacokinetics

Nicolas Charrier, Brian Clarke, Leanne Cutler, Emmanuel Demont, Colin Dingwall, Rachel Dunsdon, Julie Hawkins, Colin Howes, Julia Hubbard, Ishrut Hussain, Graham Maile, Rosalie Matico, Julie Mosley, A

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 356 KB

english, 2009

6

BACE-1 hydroxyethylamine inhibitors using novel edge-to-face interaction with Arg-296

Brian Clarke, Leanne Cutler, Emmanuel Demont, Colin Dingwall, Rachel Dunsdon, Julie Hawkins, Colin Howes, Ishrut Hussain, Graham Maile, Rosalie Matico, Julie Mosley, Alan Naylor, Alistair O’Brien, Sal

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 1.80 MB

english, 2010

7

A novel approach to the site specific delivery of potential HMG-CoA reductase inhibitors

Keith A. Menear, Dilip Patel, Valerie Clay, Colin Howes, Peter W. Taylor

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1992

Language:

english

File:

PDF, 336 KB

english, 1992

8

Estimating the prevalence of problem drug use in inner London: a discussion of three capture-recapture studies

Matthew Hickman, Stuart Cox, Julie Harvey, Samantha Howes, Michael Farrell, Martin Frischer, Gerry Stimson, Colin Taylor, Kate Tilling

Journal:

Year:

1999

Language:

english

File:

PDF, 139 KB

english, 1999

9

Rationale for targeted drug delivery

Peter W. Taylor, Colin Howes

Journal:

Year:

1991

Language:

english

File:

PDF, 838 KB

english, 1991

10

Comparative effects of angiotensin converting enzyme inhibition (perindopril) or diuretic therapy on cardiac hypertrophy and sympathetic activity following myocardial infarction in rats

Laurence G. Howes, G. Peter Hodsman, Peter R. Rowe, Colin I. Johnston

Journal:

Cardiovascular Drugs and Therapy

Year:

1991

Language:

english

File:

PDF, 1.26 MB

english, 1991

11

Oral administration of a potent and selective non-peptidic BACE-1 inhibitor decreases β-cleavage of amyloid precursor protein and amyloid-β production in vivo

Ishrut Hussain, Julie Hawkins, David Harrison, Christopher Hille, Gareth Wayne, Leanne Cutler, Tania Buck, Daryl Walter, Emmanuel Demont, Colin Howes, Alan Naylor, Philip Jeffrey, Maria I. Gonzalez, C

Journal:

Journal of Neurochemistry

Year:

2007

Language:

english

File:

PDF, 618 KB

english, 2007

12

Secondary bonding. Part 13. Aryl-tellurium(IV) and -iodine(III) acetates and trifluoroacetates. The crystal and molecular structures of bis-(p-methoxyphenyl)tellurium diacetate, �-oxo-bis[diphenyltrifluoroacetoxytellurium] hydrate, and [bis(trifluoroacetoxy)iodo]benzene

Alcock, Nathaniel W., Harrison, W. David, Howes, Colin

Journal:

Journal of the Chemical Society Dalton Transactions

Year:

1984

Language:

english

File:

PDF, 1.01 MB

english, 1984

13

Reduction of cardiovascular and thyroxine-suppressing activities of L-T3 by liver targeting with cholic acid

Zouhair F. Stephan, Edna C. Yurachek, Robin Sharif, Jong M. Wasvary, Ronald E. Steele, Colin Howes

Journal:

Biochemical Pharmacology

Year:

1992

Language:

english

File:

PDF, 511 KB

english, 1992

14

Substance misuse and psychiatric comorbidity: An overview of the opcs national psychiatric morbidity survey

Michael Farrell, Samantha Howes, Colin Taylor, Glynn Lewis, Rachel Jenkins, Paul Bebbington, Martin Jarvis, Terry Brugha, Baljit Gill, Howard Meltzer

Journal:

Addictive Behaviors

Year:

1998

Language:

english

File:

PDF, 150 KB

english, 1998

15

Second Generation of Hydroxyethylamine BACE-1 Inhibitors: Optimizing Potency and Oral Bioavailability †

Charrier, Nicolas, Clarke, Brian, Cutler, Leanne, Demont, Emmanuel, Dingwall, Colin, Dunsdon, Rachel, East, Philip, Hawkins, Julie, Howes, Colin, Hussain, Ishrut, Jeffrey, Phil, Maile, Graham, Matico,

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 1.00 MB

english, 2008

16

Synthesis and shape control of mercury selenide (HgSe) quantum dots

Howes, Philip, Green, Mark, Johnston, Colin, Crossley, Alison

Journal:

Journal of Materials Chemistry

Year:

2008

Language:

english

File:

PDF, 1.08 MB

english, 2008

17

Stereoselective Preparation of N -[( R,R )-( E )-1-(3,4-dichlorobenzyl)-3- (2-oxoazepan-3-yl)carbamoyl]allyl- N -methyl-3,5-bis(trifluoromethyl)benzamide, a Potent and Orally Active Dual Neurokinin NK 1 /NK 2 Receptor Antagonist

Gerspacher, Marc, Lewis, Christine, Ball, Howard A., Howes, Colin, Subramanian, Natarajan, Ryffel, Karin, Fozard, John R.

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 99 KB

english, 2003

18

Book Reviews

Turnbull, Paul, Brennan, Claire, Howes, Hilary, O’brien, Patricia, Winter, Christine, Paini, Anna, Chambers, Anne, Chambers, Keith S., Cotton, James, Newbury, Colin, Belgrave, Michael, Wilson, Janet,

Journal:

Journal of Pacific History

Year:

2010

Language:

english

File:

PDF, 173 KB

english, 2010

19

The stereocontrolled synthesis of a 2,3,3-trisubstituted cyclohexanone involving hydroxylactonisation of a tertiary amide

Cairns, Peter M., Howes, Colin, Jenkins, Paul R.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1990

Language:

english

File:

PDF, 878 KB

english, 1990

20

A stereocontrolled synthesis and X-ray crystal structure of a 2,3,3-trisubstituted cyclohexanone

Cairns, Peter M., Howes, Colin, Jenkins, Paul R., Russell, David R., Sherry, Lesley

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1984

Language:

english

File:

PDF, 277 KB

english, 1984

21

Drug and Alcohol Use and the Link with Homelessness: Results from a Survey of Homeless People in London

Fountain, Jane, Howes, Samantha, Marsden, John, Taylor, Colin, Strang, John

Journal:

Addiction Research & Theory

Year:

2003

Language:

english

File:

PDF, 150 KB

english, 2003

22

Genetic analysis of an endangered pine marten ( Martes americana ) population from Newfoundland using randomly amplified polymorphic DNA markers

McGowan, Colin, Howes, Lesley A, Davidson, William S

Journal:

Canadian Journal of Zoology

Year:

1999

File:

PDF, 94 KB

1999

23

The application of inelastic neutron scattering to investigate a hydrogen pre-treatment stage of an iron Fischer–Tropsch catalyst

Warringham, Robbie, Hamilton, Neil G., Silverwood, Ian P., How, Colin, Webb, Paul B., Tooze, Robert P., Zhou, Wuzong, Frost, Christopher D., Parker, Stewart F., Lennon, David

Journal:

Applied Catalysis A: General

Year:

2015

Language:

english

File:

PDF, 2.14 MB

english, 2015

24

Cyclo-(L-asparagyl-L-asparagyl)[(3S,6S)-3,6-bis(carbamoylmethyl)-piperazine-2,5-dione]: preparation and crystal structure

Howes, Colin, Alcock, Nathaniel W., Golding, Bernard T., McCabe, Richard W.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1983

Language:

english

File:

PDF, 681 KB

english, 1983

25

SPIE Proceedings [SPIE Astronomical Telescopes and Instrumentation - Orlando, FL (Wednesday 24 May 2006)] Ground-based and Airborne Instrumentation for Astronomy - A multi-object multi-field spectrometer and imager for a European ELT

Evans, Chris, Cunningham, Colin, Atad-Ettedgui, Eli, Allington-Smith, Jeremy, Assémat, Francois, Dalton, Gavin, Hastings, Peter, Hawarden, Timothy, Hook, Isobel, Ivison, Rob, Morris, Simon, Ramsay How

Year:

2006

Language:

english

File:

PDF, 407 KB

english, 2006

26

Key role of the linker in pyrene-linker-carboxylate surfactants for the efficient aqueous dispersion of multiwalled carbon nanotubes

Welsh, Daniel J., O'Driscoll, Luke J., Bailey, Steven W. D., Visontai, David, Howes, Kara, Frampton, Harry, Bryce, Martin R., Lambert, Colin J.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.12 MB

english, 2015

27

Any spare change? The income and expenditure of substance users who are sleeping rough: results from a survey in London

Fountain, Jane, Howes, Samantha, Taylor, Colin, Strang,

Journal:

Drugs and Alcohol Today

Year:

2003

Language:

english

File:

PDF, 188 KB

english, 2003

28

Reduction of the Optical Absorption of Zinc Germanium Phosphide Via Post-Growth Thermal Anneal

Ang, How-Ghee, Chng, Leng-Leng, Lee, Yiew-Wang, Flynn, Colin J., Smith, Phil C., Vere, Anthony W.

Journal:

MRS Proceedings

Year:

1999

Language:

english

File:

PDF, 350 KB

english, 1999

29

Metabolism, Excretion, and Pharmacokinetics of Selumetinib, an MEK1/2 inhibitor, in Healthy Adult Male Subjects

Dymond, Angela W., Howes, Colin, Pattison, Christine, So, Karen, Mariani, Gabriella, Savage, Mark, Mair, Stuart, Ford, Gill, Martin, Paul

Journal:

Clinical Therapeutics

Year:

2016

Language:

english

File:

PDF, 474 KB

english, 2016

30

Synergistic use of Landsat 8 OLI image and airborne LiDAR data for above-ground biomass estimation in tropical lowland rainforests

Phua, Mui-How, Johari, Shazrul Azwan, Wong, Ong Cieh, Ioki, Keiko, Mahali, Maznah, Nilus, Reuben, Coomes, David A., Maycock, Colin R., Hashim, Mazlan

Journal:

Forest Ecology and Management

Year:

2017

Language:

english

File:

PDF, 664 KB

english, 2017

31

MicroRNA Detection by DNA-Mediated Liposome Fusion

Jumeaux, Coline, Wahlsten, Olov, Block, Stephan, Kim, Eunjung, Howes, Philip D, Chandrawati, Rona, Höök, Fredrik, Stevens, Molly

Journal:

Year:

2017

Language:

english

File:

PDF, 2.48 MB

english, 2017

32

Authors' reply

Xenitidis, Kiriakos, Campbell, Colin, Ryan, Christopher James, Newton-Howes, Giles

Journal:

The British Journal of Psychiatry

Year:

2017

Language:

english

File:

PDF, 685 KB

english, 2017

33

MicroRNA Detection by DNA-Mediated Liposome Fusion

Jumeaux, Coline, Wahlsten, Olov, Block, Stephan, Kim, Eunjung, Chandrawati, Rona, Howes, Philip D., Höök, Fredrik, Stevens, Molly M.

Journal:

Year:

2018

File:

PDF, 719 KB

2018

34

A bioassay for prosulfocarb, pyroxasulfone and trifluralin detection and quantification in soil and crop residues

Khalil, Yaseen, Siddique, Kadambot H. M., Ward, Phil, Piggin, Colin, Bong, Sze How, Nambiar, Shabarinath, Trengove, Robert, Flower, Ken

Journal:

Crop and Pasture Science

Year:

2018

Language:

english

File:

PDF, 459 KB

english, 2018

35

One-year outcomes following implantation of second-generation trabecular micro-bypass stents in conjunction with cataract surgery for various types of glaucoma or ocular hypertension: multicenter, multi-surgeon study

Clement, Colin I, Howes, Frank, Ioannidis, Alexandros S, Shiu, Michael, Manning, David

Journal:

Clinical Ophthalmology

Year:

2019

File:

PDF, 541 KB

2019

36

Myosin IIA–mediated forces regulate multicellular integrity during vascular sprouting

Yoon, Christine, Choi, Colin, Stapleton, Sarah, Mirabella, Teodelinda, Howes, Caroline, Dong, Li, King, Jessica, Yang, Jinling, Oberai, Assad, Eyckmans, Jeroen, Chen, Christopher S., Weaver, Valerie M

Journal:

Molecular Biology of the Cell

Year:

2019

Language:

english

File:

PDF, 946 KB

english, 2019

37

Low dose prenatal testosterone exposure decreases the corticosterone response to stress in adult male, but not female, mice

Wilson, Hayley A., Martin, Emily R., Howes, Colin, Wasson, Cameron S., Newman, Amy E.M., Choleris, Elena, MacLusky, Neil J.

Journal:

Year:

2020

File:

PDF, 872 KB

2020

38

Ibrutinib plus CIT for R/R mature B-NHL in children (SPARKLE trial): initial safety, pharmacokinetics, and efficacy

Burke, G. A. Amos, Beishuizen, Auke, Bhojwani, Deepa, Burkhardt, Birgit, Minard-Colin, VÃ©ronique, Norris, Robin E., Kabickova, Edita, Pinarli, F. Guclu, Tacyildiz, Nurdan, Howes, Angela, Jong, Jan de

Journal:

Year:

2020

Language:

english

File:

PDF, 415 KB

english, 2020